![]() ![]() Dead space fraction calculation using the estimate from physiological variables and the ventilatory ratio at day 2 showed independent association with mortality at 30 days (odds ratio 1.28, p < 0.03 and 1.20, p < 0.03, respectively) whereas, the Harris–Benedict and Penn State estimations were not associated with mortality. ![]() Estimated dead space fraction and the ventilatory ratio at days 1 and 2 were significantly higher among non-survivors ( p < 0.01). Individual patient data from 940 ARDS patients were analyzed. The present study is a post hoc analysis of a prospective observational cohort study of ICUs of two tertiary care hospitals in the Netherlands. ![]() This study aimed to compare various methods for dead space estimation and the ventilatory ratio in patients with acute respiratory distress syndrome (ARDS) and to determine their independent values for predicting death at day 30. Indirect indices for measuring impaired ventilation, such as the estimated dead space fraction and the ventilatory ratio, have been shown to be independently associated with an increased risk of mortality. ![]()
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![]() ![]() ![]() He's not very difficult to defeat if you play your cards right. The Swine boss resides in the Warrens dungeon. ![]() A Crusader would be good as well, since his Smite ability hits Unholy monsters very hard, and the Necromancer is an Unholy enemy. A Hellion is also considered a good character to bring, as she has a stun that will almost always stun the Necromancer. It's recommended that when you fight him, you have characters that can pull him back to the frontline, as his attacks spawn a Bone Soldier enemy in the slot in front of him, and force him to move back a space.įor this reason, taking a Bounty Hunter, Occultist, or multiples of the aforementioned characters is advised, so that if he does get multiple skeletons, you can just pull him back to the front. This is considered the one of the more balanced of bosses, as he isn't too difficult (if you prepare yourself well enough) but isn't the easiest. 2x Crusader/Lepers: To hack the pews before getting to the boss, it's worth noting that Crusader has a damage bonus to Unholy enemies (Prophet).The Necromancer is one of the bosses of the Ruins dungeon.Hellion/Houndmaster/Grave Robber/Plague Doctor: Essentially you just want someone who is able to cast Blight or Bleed and preferably one that gets a damage bonus as a result too.When it comes to your party setup, we recommend using the following heroes if you plan to destroy the pews: Your Vestal will be in charge of healing while the rest of your team focuses on taking down the Prophet as soon as possible. ![]() The Arbalest and Bounty Hunter have damage bonus skills against marked targets, and the Grave Robber has damage bonus skills against marked and blighted targets. If you plan to ignore the pews, stack Bleed and Blight on the Prophet and also make sure you Mark him. Hellion/Houndmaster: Can attack position four/inflict Bleed.(The Bounty Hunter can also do this, but has a weaker attack for position four.) Arbalest: To Mark the Prophet/can attack position four.Grave Robber/Plague Doctor: Can attack position four and inflict Blight.When it comes to your party setup, we recommend using the following heroes if you plan to ignore the pews: ![]() |
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